Thermo Fisher Scientific BEX2 Monoclonal Antibody (OTI1H3), TrueMAB
인간 BEX2 단백질을 인식하는 Mouse IgG1 단일클론 항체로 Western blot에 적합. 동결건조 형태로 제공되며 PBS buffer에 trehalose 함유. 종양 억제 관련 BEX2 연구 및 단백질 발현 분석에 활용 가능.
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Applications
- Western Blot (WB)
Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1H3 |
| Immunogen | Full length human recombinant protein of human BEX2 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
The BEX2 gene belongs to the brain expressed X-linked gene family. The encoded protein interacts with the transcription factor LIM domain only 2 (LMO2) in a DNA-binding complex that recognizes the E-box element and promotes transcription.
This gene acts as a tumor suppressor silenced in human glioma. In breast cancer cells, BEX2 modulates apoptosis in response to estrogen and tamoxifen, enhancing the anti-proliferative effect of tamoxifen.
Multiple transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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