Thermo Fisher Scientific RNF41 Monoclonal Antibody (OTI2C1), TrueMAB

Thermo Fisher Scientific RNF41 Monoclonal Antibody (OTI2C1), TrueMAB

Applications

• Western Blot (WB)

Tested Dilution: 1:2,000

Product Specifications

Product Specific Information

For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of about 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (recommended: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).

Target Information

The RING-type zinc finger motif is a conserved cysteine-rich domain capable of binding two zinc atoms, found in various viral and eukaryotic proteins. These proteins are typically involved in the ubiquitination pathway of protein degradation.
Nrdp1, also known as RNF41 (RING finger protein 41), SBBI03, or FLRF, is a 317 amino acid protein containing one RING-type zinc finger and one SIAH-type zinc finger. Expressed in testis, ovary, and prostate, Nrdp1 functions as an E3 ubiquitin-protein ligase, transferring ubiquitin from E2 conjugating enzymes to target substrates for degradation. It specifically interacts with ErbB-3 and UBPY, promoting their proteasomal degradation.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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