Thermo Fisher Scientific RNF41 Monoclonal Antibody (OTI2C1), TrueMAB
RNF41 단백질을 인식하는 Mouse IgG1 단일클론 항체로 Western blot에 최적화됨. 인간, 생쥐, 랫트 반응성. 동결건조 형태로 공급되며, 재구성 후 1 mg/mL 농도 유지. 단백질 분해 관련 연구용으로 적합.
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Thermo Fisher Scientific RNF41 Monoclonal Antibody (OTI2C1), TrueMAB
Applications
- Western Blot (WB)
Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2C1 |
| Immunogen | Full length human recombinant protein of human RNF41 produced in E.coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of about 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (recommended: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
The RING-type zinc finger motif is a conserved cysteine-rich domain capable of binding two zinc atoms, found in various viral and eukaryotic proteins. These proteins are typically involved in the ubiquitination pathway of protein degradation.
Nrdp1, also known as RNF41 (RING finger protein 41), SBBI03, or FLRF, is a 317 amino acid protein containing one RING-type zinc finger and one SIAH-type zinc finger. Expressed in testis, ovary, and prostate, Nrdp1 functions as an E3 ubiquitin-protein ligase, transferring ubiquitin from E2 conjugating enzymes to target substrates for degradation. It specifically interacts with ErbB-3 and UBPY, promoting their proteasomal degradation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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