Thermo Fisher Scientific SERPINA3 Monoclonal Antibody (71A1)
인간 SERPINA3 단백질을 인식하는 단클론 항체로, Western blot 및 IHC(파라핀) 분석에 적합합니다. 인간 혈장 유래 단백질로 면역화되었으며, 비결합형 액상 형태로 제공됩니다. 알츠하이머 연구 등 신경퇴행성 질환 연구에 활용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.5 µg/mL | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Published Species | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 71A1 |
| Immunogen | Protein purified from Human plasma |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.0 mg/mL |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_1954828 |
Product Specific Information
A suggested positive control for this product is human plasma.
Target Information
SERPINA encodes Alpha 1-ACT, an early-stage acute-phase plasma protein and a serpin that preferentially inactivates chymotrypsin, cathepsin G, and chymase. Alpha-1-ACT, a serine protease inhibitor, is tightly associated with amyloid plaques in Alzheimer’s disease (AD) and in normal aged human and monkey brain. Regulation of the serine proteases and their inhibitors plays an important role in neuromuscular differentiation. Prostate specific antigen (PSA), a chymotrypsin-like serine protease, is predominantly complexed to Alpha-1-ACT.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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