Thermo Fisher Scientific IKK alpha Monoclonal Antibody (3A11)
IKK alpha 단백질 검출용 마우스 단클론 항체로, Western blot과 Immunoprecipitation에 적합합니다. HeLa 세포를 양성 대조군으로 권장하며, 비결합형 액상 형태로 제공됩니다. NF-κB 신호전달 연구에 활용 가능합니다.
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Thermo Fisher Scientific IKK alpha Monoclonal Antibody (3A11)
Applications and Tested Dilutions
- Western Blot (WB): 2 µg/mL
- Immunoprecipitation (IP): 2 µg
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 3A11 |
| Immunogen | Synthetic peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2 mg/mL |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2079398 |
Product Specific Information
A suggested positive control for this product is HeLa cells.
Target Information
CHUK (IKK alpha) is a serine/threonine kinase involved in signal transduction and cellular communication. It is part of the cytokine-activated protein complex that inhibits the NF-kappa B complex.
IKK alpha, together with IKK beta and the regulatory protein NEMO (IKK gamma), phosphorylates IkB proteins, targeting them for ubiquitin-mediated degradation.
This protein plays a role in various cellular processes, particularly inflammation and cell survival.
Usage Notes
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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