Thermo Fisher Scientific ADAMTS5 Polyclonal Antibody
ADAMTS5 단백질을 검출하기 위한 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 IHC, ELISA에 사용 가능. 사람, 소, 돼지 시료 반응성. 항원 친화 크로마토그래피로 정제된 고순도 항체. 연구용으로만 사용.
- 카탈로그번호
- PA11751A
- 판매단위
- pk
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Thermo Fisher Scientific ADAMTS5 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1 µg/mL | – |
| Immunohistochemistry (IHC) | – | 3 publications |
| ELISA | – | 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Bovine, Human, Pig |
| Published Species | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues C K(636) N G Y Q S D A K G V K T F(649) of human ADAMTS5 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 1 mg/mL BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_1070008 |
Product Specific Information
PA1-1751A detects ADAMTS5 from porcine, bovine, and human samples.
This antibody is specific for ADAMTS5 and shows no cross-reactivity with other ADAMTS family members.
PA1-1751A has been successfully used in Western blot procedures.
- Detects a major band at ~68 kDa from porcine cartilage extract.
- Detects a major band at ~85 kDa for human recombinant ADAMTS5.
- Depending on C-terminal processing, several smaller bands may also be observed.
The immunogen is a synthetic peptide corresponding to residues C K(636) N G Y Q S D A K G V K T F(649) of human ADAMTS5.
This polyclonal antibody has also been referred to as JSCKNG.
Target Information
ADAMTS5 (A Disintegrin And Metalloproteinase with Thrombospondin-5 motif), also known as Implantin or Aggrecanase 2, is a member of the ADAMs metalloproteinase family containing thrombospondin repeats.
Initially identified as a protein elevated during the peri-implantation period in mice and later found elevated in arthritic synovium, ADAMTS5 is expressed in human and mouse tissues including heart, lung, cervix, uterus, ovary, brain, cartilage, and chondroblastoma cell lines.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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