Thermo Fisher Scientific SH2B3 Monoclonal Antibody (OTI2C9), TrueMAB
SH2B3 단백질을 인식하는 Mouse IgG1 단일클론 항체로, Western blot, ICC/IF, Flow Cytometry에 사용 가능. 동결건조 형태로 제공되며 재구성 후 약 1 mg/mL 농도로 사용. 인간 SH2B3 단백질에 반응하며 연구용으로 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2C9 |
| Immunogen | Full length human recombinant protein of human SH2B3 produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
- For conjugation experiments, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
The SH2B3 gene encodes a member of the SH2B adaptor family involved in various signaling activities mediated by growth factor and cytokine receptors. The encoded protein acts as a negative regulator of cytokine signaling and is essential for hematopoiesis. Mutations in SH2B3 are associated with susceptibility to celiac disease type 13 and insulin-dependent diabetes mellitus.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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