Thermo Fisher Scientific RAB3IP Monoclonal Antibody (OTI5G4), TrueMAB
RAB3IP 단백질을 인식하는 Mouse IgG1 단일클론 항체로 Western blot에 적합. HEK293T 세포에서 생산된 full-length 인간 RAB3IP 항원을 사용한 TrueMAB 제품. 액상 형태로 1 mg/mL 농도이며 PBS/BSA/glycerol 버퍼에 보관. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI5G4 |
| Immunogen | Full length human recombinant protein of human RAB3IP produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Target Information
Guanine nucleotide exchange factor (GEF) which may activate RAB8A and RAB8B.
Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form.
Mediates the release of GDP from RAB8A and RAB8B but not from RAB3A or RAB5.
Modulates actin organization and promotes polarized transport of RAB8A-specific vesicles to the cell surface.
Together with RAB11A, RAB8A, the exocyst complex, PARD3, PRKCI, ANXA2, CDC42 and DNMBP promotes transcytosis of PODXL to the apical membrane initiation sites (AMIS), apical surface formation and lumenogenesis.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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