Thermo Fisher Scientific GLT-1 Recombinant Rabbit Monoclonal Antibody (PS01-62)

Applications

Western Blot (WB)

• Tested Dilution: 1:1,000

Immunohistochemistry (Paraffin) (IHC (P))

• Tested Dilution: 1:1,000

Product Specifications

Product Specific Information

• Positive control: Mouse brain tissue lysate, rat brain tissue lysate, mouse cerebellum tissue lysate, mouse brain tissue, mouse cerebellum tissue, rat cerebellum tissue
• Predicted band size: 62 kDa
• Subcellular Location: Cell membrane

Target Information

Excitatory amino acid transporter 2 (EAAT2) is a membrane-bound solute transporter responsible for clearing the excitatory neurotransmitter glutamate from the extracellular space at synapses in the central nervous system. Proper glutamate clearance prevents neuronal damage from excessive receptor activation. Mutations or reduced expression of EAAT2 are associated with amyotrophic lateral sclerosis (ALS). Alternatively spliced transcript variants of this gene have been identified.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.