Thermo Fisher Scientific KLF11 Monoclonal Antibody (OTI4H7)
KLF11 단백질을 인식하는 Thermo Fisher Scientific의 Mouse Monoclonal 항체. Western blot에 적합하며, Human 시료에 반응. 고순도 Affinity Chromatography 정제 및 안정한 PBS/BSA/glycerol buffer로 장기 보관 가능.
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Applications
- Western Blot (WB): 1:500–1:2,000 dilution
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4H7 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–274 of KLF11 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2724572 |
Target Information
The protein encoded by the KLF11 gene is a zinc finger transcription factor that binds to SP1-like sequences in epsilon- and gamma-globin gene promoters. This binding inhibits cell growth and induces apoptosis.
Defects in this gene are associated with maturity-onset diabetes of the young type 7 (MODY7).
Three transcript variants encoding two different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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