Thermo Fisher Scientific SULT2A1 Recombinant Rabbit Monoclonal Antibody (4A3H6)
Thermo Fisher Scientific의 SULT2A1 Recombinant Rabbit Monoclonal Antibody (4A3H6)은 인간 및 랫트 시료에 반응하며, Western blot, ICC/IF, ELISA에 적합합니다. 고순도 친화 크로마토그래피로 정제된 액상 항체로, 간 및 부신 조직의 SULT2A1 단백질 연구에 유용합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 4A3H6 |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 180–285 of human SULT2A1 (Q06520) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.85 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 0.05% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2912028 |
Product Specific Information
- Positive test controls include: HepG2
- Immunogen sequence:
LLLSYEELKQ DTGRTIEKIC QFLGKTLEPE ELNLILKNSS FQSMKENKMS NYSLLSVDYV VDKAQLLRKG VSGDWKNHFT VAQAEDFDKL FQEKMADLPR ELFPWE
Target Information
SULT1 sulfotransferases exhibit N-sulfating activities of carcinogenic heterocyclic amines and are selective toward phenols, whereas SULT2 enzymes prefer hydroxysteroids and SULT3 family members are selective for N-substituted aryl and alicyclic compounds.
SULT2A1 catalyzes the sulfonation of procarcinogen xenobiotics, hydroxysteroids, and bile acids, and is highly expressed in adrenal and liver tissues. It plays a role in hepatic cholesterol homeostasis.
SULT2B1 consists of two isoforms, SULT2B1a and SULT2B1b, transcribed from the same gene by alternative splicing. Both isoforms are highly selective for the sulfation of 3β-hydroxysteroids such as pregnenolone, epiandrosterone, DHEA, and androstenediol.
SULT2B1b is expressed in prostate, skin, placenta, and lung.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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