Thermo Fisher Scientific SULT2A1 Recombinant Rabbit Monoclonal Antibody (4A3H6)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

Immunocytochemistry (ICC/IF)

1:50-1:200

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Rat

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

4A3H6

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 180-285 of human SULT2A1 (Q06520). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:SULT2A1,uniProtId:Q06520-1,ncbiNodeId:9606,antigenRange:180-285,antigenLength:285,antigenImageFileName:MA5-42887_SULT2A1_Q06520-1_Rabbit.svg,antigenImageFileNamePDP:MA5-42887_SULT2A1_Q06520-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.85 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 0.05% BSA, 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2912028

Product Specific Information

Positive test controls include: HepG2.

Immunogen sequence: LLLSYEELKQ DTGRTIEKIC QFLGKTLEPE ELNLILKNSS FQSMKENKMS NYSLLSVDYV VDKAQLLRKG VSGDWKNHFT VAQAEDFDKL FQEKMADLPR ELFPWE

Target Information

SULT1 sulfotransferases exhibit N-sulfating activities of carcinogenic heterocyclic amines, and are selective toward phenols, whereas SULT2 enzymes prefer hydroxysteroids and SULT3 family members are selective for N-substituted aryl and alicyclic compounds. SULT2A1 catalyzes the sulfonation of procarcinogen xenobiotics, hydroxysteroids and bile acids, and is highly expressed in adrenal and liver tissues. SULT2A1 plays a role in hepatic cholesterol homeostasis. SULT2B1 consists of two isoforms, SULT2B1a and SULT2B1b, which are transcribed from the same gene by alternative splicing of their first exons. Both isoforms are highly selective for the sulphation of 3b-hydroxysteroids such as pregnenolone, epiandrosterone, DHEA and androstenediol. SULT2B1b is expressed in prostate, skin, placenta and lung.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.