Thermo Fisher Scientific SOX10 Recombinant Rabbit Monoclonal Antibody (2V5D6)
SOX10 단백질을 인식하는 재조합 토끼 단클론 항체로, Western blot, ICC/IF, ELISA 등에 적합합니다. 인간, 마우스, 랫트 시료에서 반응하며, 높은 특이성과 재현성을 제공합니다. 연구용으로 사용되며, 신경 및 발생 연구에 유용합니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:6,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:400 |
| ELISA | 1 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 2V5D6 |
| Immunogen | A synthetic peptide corresponding to a sequence within amino acids 350–450 of human SOX10 (P56693) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 0.05% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2912031 |
Product Specific Information
Positive test controls include: HeLa, HT-29, SH-SY5Y, Mouse large intestine, Mouse brain, Mouse heart, Rat brain, Rat heart.
The target is typically localized in the cytoplasm and nucleus.
Immunogen sequence:
VDAKAQVKTE TAGPQGPPHY TDQPSTSQIA YTSLSLPHYG SAFPSISRPQ FDYSDHQPSG PYYGHSGQAS GLYSAFSYMG PSQRPLYTAI SDPSPSGPQS H
Target Information
SOX10 is a member of the SOX (SRY-related HMG-box) family of transcription factors involved in embryonic development and cell fate determination. It may act as a transcriptional activator through complex formation with other proteins and functions as a nucleocytoplasmic shuttle protein. SOX10 plays an essential role in neural crest and peripheral nervous system development.
Mutations in SOX10 are associated with Waardenburg-Shah and Waardenburg-Hirschsprung diseases.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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