Thermo Fisher Scientific Bestrophin 2 Polyclonal Antibody
Bestrophin 2 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체. WB 및 IHC(P) 실험에 적합하며, Human, Mouse, Rat 시료에서 반응. 1 mg/mL 농도의 액상 제품으로 -20°C 보관. Affinity chromatography로 정제됨.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human BEST2 (Accession Q8NFU1), corresponding to amino acid residues T429–E479 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2899536 |
Product Specific Information
This antibody detects endogenous levels of total Bestrophin 2.
Target Information
Best2 forms calcium-sensitive chloride channels and is permeable to bicarbonate. The Best2 gene is part of the bestrophin gene family of anion channels, sharing a conserved exon-intron structure but distinct 3' ends. Bestrophins are transmembrane proteins rich in aromatic residues, including an invariant arg-phe-pro motif. Mutations in the Best2 gene are associated with vitelliform macular dystrophy. Best2 is primarily expressed in the retinal pigment epithelium and colon. Diseases associated with BEST2 include Vitelliform Macular Dystrophy and Bestrophinopathy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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