Thermo Fisher Scientific Complement C5a Monoclonal Antibody (561)
인간 C5/C5a 단백질을 검출하는 Mouse IgG2a 단일클론 항체. Western blot, ELISA, IP, 기능적 분석에 사용 가능. Protein G 정제, PBS+BSA 용액 형태로 제공되며 보존제 없음. 연구용으로만 사용.
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Thermo Fisher Scientific Complement C5a Monoclonal Antibody (Clone 561)
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:50 |
| ELISA | 1:50 |
| Immunoprecipitation (IP) | 1:50 |
| Functional Assay | 1:50 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 561 |
| Immunogen | N-terminus of C5 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS with 0.1% BSA |
| Contains | No preservative |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_1073835 |
Product Specific Information
- MA1-40159 detects C5/C5a from human samples.
- Successfully used in ELISA, functional assays, immunoprecipitation, and Western blot.
- ELISA: The antibody 561 can be used as detector in ELISA.
- Immunogen is the N-terminus of C5.
- Endotoxin <24 EU/mg.
Target Information
Complement component 5 (C5) is a key protein in inflammatory and cell-killing processes. It consists of alpha and beta polypeptide chains linked by a disulfide bridge. Upon activation, C5 is cleaved to produce C5a, an anaphylatoxin with potent spasmogenic and chemotactic activity, and C5b, which participates in forming the membrane attack complex with C6 and other complement components. Mutations in C5 are associated with complement component 5 deficiency, leading to recurrent infections, and are linked to liver fibrosis and rheumatoid arthritis susceptibility.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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