Thermo Fisher Scientific MMP10 Recombinant Rabbit Monoclonal Antibody (24 H24L21)
Recombinant rabbit monoclonal antibody targeting MMP10, validated for Western blot. High specificity and lot-to-lot consistency with Expi293 expression system. Suitable for human and rat samples. Supplied as liquid, 0.5 mg/mL, Protein A purified, store...
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Applications
Western Blot (WB)
- Tested Dilution: 1–3 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | Expi293 |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 24 H24L21 |
| Immunogen | Recombinant protein corresponding to amino acids 282–476 of human MMP10 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C avoiding freeze/thaw cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2532460 |
Product Specific Information
This antibody is predicted to react with mouse, rat, non-human primate, and rabbit based on sequence homology.
Intact IgG appears on a non-reducing gel as a ~150 kDa band and upon reduction generates a ~25 kDa light chain band and a ~50 kDa heavy chain.
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning specific antibody DNA sequences from immunoreactive rabbits. Individual clones are screened to select the best candidates for production.
Advantages of recombinant rabbit monoclonal antibodies:
- Better specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulations
- Broader immunoreactivity due to larger rabbit immune repertoire
Target Information
MMP10 belongs to the matrix metalloproteinase family and is secreted in its pro form, further modified by extracellular proteinases.
As a metalloproteinase, MMP10 requires zinc and calcium as cofactors for activity. It is involved in activation of pro-collagenase, catabolism of collagen, degradation of fibronectin, and tissue remodeling.
In humans, the MMP10 gene is located on chromosome 11.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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