Thermo Fisher Scientific CD89 Polyclonal Antibody
인간 CD89(FCAR)에 반응하는 Rabbit Polyclonal Antibody로, Western blot에 적합합니다. 합성 펩타이드 면역원으로 제작되었으며, 액상 형태로 1 mg/mL 농도입니다. PBS 및 50% glycerol에 보관하며, 연구용으로만 사용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human FCAR (Accession P24071), corresponding to amino acid residues N177–N227 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2899856 |
Product Specific Information
Antibody detects endogenous levels of total FCAR.
Target Information
This gene belongs to the immunoglobulin gene superfamily and encodes a receptor for the Fc region of IgA.
The receptor is a transmembrane glycoprotein found on myeloid lineage cells such as neutrophils, monocytes, macrophages, and eosinophils, mediating immune responses to pathogens.
It interacts with IgA-opsonized targets and triggers defense processes including:
- Phagocytosis
- Antibody-dependent cell-mediated cytotoxicity
- Release of inflammatory mediators
Multiple alternatively spliced transcript variants encoding different isoforms have been reported.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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