Thermo Fisher Scientific PARP14 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:3,000

View 1 publication 1 publication

Immunohistochemistry (Paraffin) (IHC (P))

Assay-dependent

-

Immunoprecipitation (IP)

1:100-1:500

-

Product Specifications

Species Reactivity

Human

Published species

Not Applicable

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein encompassing a sequence within the C-terminus region of human PARP14. The exact sequence is proprietary. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:PARP14,uniProtId:Q460N5-6,ncbiNodeId:9606,antigenRange:1801,antigenLength:1801,antigenImageFileName:PA5-78512_PARP14_Q460N5-6_Rabbit.svg,antigenImageFileNamePDP:PA5-78512_PARP14_Q460N5-6_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.29 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7, with 20% glycerol

Contains

0.025% ProClin 300

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2736325

Product Specific Information

Positive Control: U87-MG, SK-N-SH, SK-N-AS

Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Target Information

Poly [ADP-ribose] polymerase 14 (PARP14) is a B aggressive lymphoma protein belonging to the PARP protein family. Poly ADP ribosylation is a DNA damage dependent post translational modification of histones and other nuclear proteins that mediates DNA repair. PARP proteins with a macrodomain are also involved in gene expression through transcriptional regulation. PARP14 controls STAT6 dependent transcription by enhancing binding to the promoter in the presence of a positive signal (i.e. IL4 stimulation).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.