Thermo Fisher Scientific PARP14 Polyclonal Antibody
PARP14 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, IHC, IP 등 다양한 응용 가능. 인간 종에 반응하며 항원 친화 크로마토그래피로 정제됨. 액상 형태, 장기 보관 시 -20°C 권장.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:3,000
- View 1 publication
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: Assay-dependent
- View publication
Immunoprecipitation (IP)
- Tested Dilution: 1:100–1:500
- View publication
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein encompassing a sequence within the C-terminus region of human PARP14. The exact sequence is proprietary. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.29 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 20% glycerol |
| Contains | 0.025% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2736325 |
Product Specific Information
- Positive Control: U87-MG, SK-N-SH, SK-N-AS
- Store product as a concentrated solution.
- Centrifuge briefly prior to opening the vial.
Target Information
Poly [ADP-ribose] polymerase 14 (PARP14) is a B aggressive lymphoma protein belonging to the PARP protein family. Poly ADP ribosylation is a DNA damage–dependent post-translational modification of histones and other nuclear proteins that mediates DNA repair. PARP proteins with a macrodomain are also involved in gene expression through transcriptional regulation. PARP14 controls STAT6-dependent transcription by enhancing promoter binding in the presence of a positive signal (e.g., IL4 stimulation).
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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