Thermo Fisher Scientific RNF3 Polyclonal Antibody
Thermo Fisher Scientific의 RNF3 Polyclonal Antibody는 인간 RNF3 단백질을 인식하는 염소 유래 IgG 항체로, Western blot에 최적화되어 있습니다. 0.5 mg/mL 농도의 액상 형태이며, TBS(pH 7.3) 버퍼에 0.5% BSA와 0.02% sodium azide가 포함되어 있습니다. 연구용으로만 사용 가능합니다.
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 0.5–2 µg/mL
- Publications: 없음
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide with sequence PLLLHYRPKMDLL, from C Terminus of the protein sequence according to NP_006306 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | IgG fraction |
| Storage buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2065879 |
Product Specific Information
- Recommended positive controls: The peptide used to generate this antibody is available for purchase (GTX23892-PEP).
- Store product as a concentrated solution.
- Centrifuge briefly prior to opening the vial.
Target Information
Phosphorylase kinase is a hexadecameric enzyme comprised of four copies of four subunits encoded by PHKA, PHKB, PHKG, and PH genes. This serine/threonine-specific kinase converts glycogen phosphorylase b to glycogen phosphorylase a, releasing glucose-1-phosphate from glycogen.
PHKB (Phosphorylase b kinase regulatory subunit beta) is a 1093 amino acid subunit with regulatory functions controlled by phosphorylation.
Defects in PHKB cause glycogen storage disease type 9B (phosphorylase kinase deficiency of liver and muscle), characterized by mild hepatomegaly, slightly elevated transaminase and plasma lipids, no clinical muscle involvement, and improvement with age.
Four isoforms of PHKB are produced by alternative splicing events.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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