Thermo Fisher Scientific MINA53 Polyclonal Antibody
Human MINA53 단백질을 표적으로 하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, IHC, ICC/IF에 적합하며, 항원 친화 크로마토그래피로 정제된 액상 시약. 세포 증식 및 Myc 관련 유전자 연구에 활용 가능.
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Thermo Fisher Scientific MINA53 Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein fragment corresponding to amino acids 105–409 of Human MINA53 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.1M Tris Glycine, pH 7, with 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C avoiding freeze/thaw cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2548703 |
Product Specific Information
- Recommended positive controls: 293T, A431, Jurkat, Raji
- Predicted reactivity: Human (99%), Rat (80%), Rhesus Monkey (98%), Bovine (83%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
MINA is a nuclear-localized, myc-inducible protein involved in mammalian cell proliferation. Knockdown of MINA in cancer cell lines such as SW680 inhibits cell growth, suggesting its potential as a therapeutic target.
MINA regulates genes associated with cell adhesion and metabolism, some of which are Myc-regulated, and others such as EGFR, IL-6, and HGF that are not. It also represses IL-4 expression in T cells, indicating a role in T cell differentiation and Th2 bias.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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