
Thermo Fisher Scientific TMEM259 Polyclonal Antibody
TMEM259 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western blot 및 IHC(paraffin) 실험에 적합. Human에 반응하며 Mouse와 Rat에도 예측 반응. 항원 친화 크로마토그래피로 정제되어 높은 특이성과 재현성을 제공. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:5,000–1:20,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:100–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein fragment corresponding to a region within amino acids 1–257 of Human Membralin |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 1% BSA, 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2548704 |
Product Specific Information
- Recommended positive controls: K562, THP-1, HL-60
- Predicted reactivity: Mouse (84%), Rat (84%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Human membralin is unique and does not share significant sequence homology with other human genes, only membralins of other species.
The membralin gene contains 11 exons encoding at least two spliced variants in human cancer.
- Membralin-1 (long form): all 11 exons, 620 amino acids
- Membralin-3 (short form): all exons except exon 10, 408 amino acids
Expression of different membralin isoforms depends on tissue type.
- Membralin-1: expressed in ovarian and colorectal carcinomas
- Membralin-3: expressed in breast and pancreatic carcinomas
Recent studies suggest that membralin is a novel tumor-associated marker in ovarian serous carcinomas.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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