Thermo Fisher Scientific GPR37 Polyclonal Antibody
GPR37 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB 및 IHC(P) 실험에 적합합니다. 인간과 생쥐 시료에 반응하며, KLH 결합 합성 펩타이드로 면역화되었습니다. 고순도 액상 형태로 4°C 또는 -20°C에서 안정적으로 보관 가능합니다.
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000
- Publications: View 1 publication
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:100
- Publications: —
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide between 217–246 amino acids from the C-terminal region of human Pael-R (GPR37) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2112516 |
Target Information
Parkinson’s disease is the second most common neurodegenerative disorder after Alzheimer’s. About 1% of people over 65 and 3% over 75 are affected. Mutations in Park2 are the most common genetic cause identified to date. Park2 may play a role in the ubiquitin-mediated proteolytic pathway, and mutations can lead to autosomal recessive juvenile parkinsonism. Alternative splicing produces three known isoforms of undetermined function. Panneuronal expression of Parkin substrate Pael-R leads to age-dependent degeneration of dopaminergic neurons in Drosophila, while coexpression of Parkin degrades Pael-R and suppresses its toxicity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지 파일: PA5-13413_GPR37_O15354-1_Rabbit_PDP.jpeg)
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