Thermo Fisher Scientific GPR37 Polyclonal Antibody
GPR37 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB 및 IHC(P) 실험에 적합합니다. 인간 및 마우스 반응성을 가지며, 고순도 Protein A 및 항원 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- PA513412
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific GPR37 Polyclonal Antibody
Applications
Western Blot (WB)
- Tested Dilution: 1:1,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide between 97–126 amino acids from the N-terminal region of human Pael-R (GPR37) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2294811 |
Target Information
Parkinson’s disease is the second most common neurodegenerative disorder after Alzheimer’s. Approximately 1% of people over 65 and 3% over 75 are affected. Mutations in the Park2 gene are among the most common causes of Parkinson’s disease. Park2 may function in the ubiquitin-mediated proteolytic pathway. Mutations are associated with autosomal recessive juvenile parkinsonism. Alternative splicing yields three isoforms with undetermined functions. Panneuronal expression of Parkin substrate Pael-R induces age-dependent degeneration of Drosophila dopaminergic neurons; coexpression of Parkin degrades Pael-R and suppresses its toxicity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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