Thermo Fisher Scientific DR3 Polyclonal Antibody
Rabbit polyclonal antibody targeting human DR3 for research use. Suitable for WB, IHC(F), and ICC/IF applications. Unconjugated, liquid form, 1 mg/mL concentration. Store at 4°C short term or -20°C long term to maintain stability.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific DR3 Polyclonal Antibody
Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1–5 µg/mL | - |
| Immunohistochemistry (Frozen) (IHC (F)) | Assay-dependent | - |
| Immunocytochemistry (ICC/IF) | Assay-dependent | - |
Product Specifications
| Property | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide from extracellular domain of human DR3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_1957924 |
Product Specific Information
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
DR3 (TNFRSF25) is a member of the TNF-receptor superfamily, expressed predominantly in lymphocyte-rich tissues. It plays a role in lymphocyte homeostasis, stimulates NF-kappa B activity, and regulates apoptosis. Signal transduction occurs via death domain-containing adaptor proteins. Knockout studies in mice suggest DR3/TNFRSF25 contributes to the removal of self-reactive T cells in the thymus. Multiple alternatively spliced transcript variants exist, with most encoding potentially secreted molecules. Upon T-cell activation, alternative splicing produces full-length, membrane-bound isoforms, which may regulate lymphocyte proliferation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.