Thermo Fisher Scientific ENO1 Polyclonal Antibody
Thermo Fisher Scientific의 ENO1 Polyclonal Antibody는 인간 비신경성 Enolase 전체 길이 항원을 면역원으로 한 토끼 IgG 폴리클로날 항체입니다. WB, IHC, ICC, ELISA 등 다양한 응용에 사용 가능하며, ENO1 단백질 연구 및 암, 저산소성 손상, 자가면역 질환 관련 연구에 적합합니다.
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- PA130493
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:25–1:100 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:25–1:100 |
| Immunocytochemistry (ICC/IF) | 5 µg/mL |
| ELISA | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Published Species | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Full-length human non-neuronal Enolase |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 5 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_1958429 |
Product Specific Information
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Enolase (2-phosphogly-cerate hydrolyase or phosphopyruvate hydrates) is a glycolytic enzyme that catalyzes the conversion of 2-phosphoglycerate to phosphoenolpyruvate. It consists of three subunits: alpha, beta, and gamma.
Non-neuronal Enolase (ENO1) is a mammalian isoform composed of two alpha subunits. The ENO1 gene also encodes a shorter monomeric structural lens protein, tau-crystallin.
ENO1 functions in glycolysis and plays roles in growth control, hypoxia tolerance, allergic responses, and fibrinolytic activity by acting as a plasminogen receptor on cell surfaces such as leukocytes and neurons.
It stimulates immunoglobulin production and serves as a diagnostic marker for various tumors and hypoxic brain injury. It is also associated with endometriosis and autoimmune diseases such as Hashimoto encephalopathy (HE) and Hashimoto thyroiditis (HT).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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