Thermo Fisher Scientific MRP1 Polyclonal Antibody
MRP1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB 및 IHC(P) 실험에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 동결건조 상태로 제공됩니다. 재구성 후 500 µg/mL 농도로 사용 가능하며, 연구용으로만 사용됩니다.
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Thermo Fisher Scientific MRP1 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.1–0.5 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 0.5–1 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to human MRP1 (1514–1531aa, LLQQRGLFYSMAKDAGLV) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 500 µg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 5 mg BSA |
| Contains | 0.05 mg sodium azide, 0.05 mg thimerosal |
| Storage Conditions | −20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2745810 |
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Target Information
The MRP1 gene encodes a member of the ATP-binding cassette (ABC) transporter superfamily. These proteins mediate the transport of various molecules across cell membranes. MRP1 belongs to the MRP subfamily associated with multidrug resistance. It functions as a multispecific organic anion transporter, handling substrates such as oxidized glutathione, cysteinyl leukotrienes, and activated aflatoxin B1. It also transports glucuronides and sulfate conjugates of steroid hormones and bile salts. Alternative splicing results in several variants that preserve the original open reading frame.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지 파일: PA5-78694_MRP1_P33527-1_Rabbit.svg, PA5-78694_MRP1_P33527-1_Rabbit_PDP.jpeg)
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