
Thermo Fisher Scientific ZPR1 Polyclonal Antibody
Human ZPR1 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot과 ELISA에 적합합니다. Affinity Chromatography로 정제되었으며, PBS 및 50% glycerol buffer에 보존됩니다. -20°C에서 보관하며, 연구용으로만 사용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing amino acids 110–459 of human ZPR1 (NP_003895.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.07 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2806169 |
Product Specific Information
Immunogen sequence:
LEDMNREVVK TDSAATRIPE LDFEIPAFSQ KGALTTVEGL ITRAISGLEQ DQPARRANKD ATAERIDEFI VKLKELKQVA SPFTLIIDDP SGNSFVENPH APQKDDALVI THYNRTRQQE EMLGLQEEAP AEKPEEEDLR NEVLQFSTNC PECNAPAQTN MKLVQIPHFK EVIIMATNCE NCGHRTNEVK SGGAVEPLGT RITLHITDAS DMTRDLLKSE TCSVEIPELE FELGMAVLGG KFTTLEGLLK DIRELVTKNP FTLGDSSNPG QTERLQEFSQ KMDQIIEGNM KAHFIMDDPA GNSYLQNVYA PEDDPEMKVE RYKRTFDQNE ELGLNDMKTE GYEAGLAPQR
Positive Samples: U-87MG
Cellular Location: Cajal body, Cell projection, Cytoplasm, Nucleus, axon, gem, growth cone, nucleolus, perinuclear region
Target Information
The protein encoded by this gene is found in the cytoplasm of quiescent cells but translocates to the nucleolus in proliferating cells. It interacts with survival motor neuron protein (SMN1) to enhance pre-mRNA splicing and to induce neuronal differentiation and axonal growth. Defects in this gene or SMN1 can cause spinal muscular atrophy. Two transcript variants encoding different isoforms have been identified.
(Source: RefSeq, Nov 2015)
⚠ WARNING: This product can expose you to chemicals including mercury, known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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