
Thermo Fisher Scientific VPS4B Polyclonal Antibody
VPS4B 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체로, Western blot과 ELISA에 적합합니다. 인간 VPS4B의 1-130 아미노산 서열을 기반으로 제작되었으며, PBS/glycerol 용액에 보존됩니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1–130 of human VPS4B (NP_0048602) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.72 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2806171 |
Product Specific Information
Immunogen sequence:
MSSTSPNLQK AIDLASKAAQ EDKAGNYEEA LQLYQHAVQY FLHVVKYEAQ GDKAKQSIRA KCTEYLDRAE KLKEYLKNKE KKAQKPVKEG QPSPADEKGN DSDGEGESDD PEKKKLQNQL QGAIVIERPN
Positive Samples: Mouse kidney, Mouse heart
Cellular Location: Late endosome membrane, Peripheral membrane protein, Prevacuolar compartment membrane
Target Information
The VPS4B protein is a member of the AAA protein family (ATPases associated with diverse cellular activities) and is homologous to the yeast Vps4 protein. In humans, two paralogs have been identified, sharing high amino acid sequence similarity with yeast Vps4 and mouse Skd1 proteins. Functional studies show both human paralogs associate with endosomal compartments and are involved in intracellular protein trafficking. The VPS4B gene is located on chromosome 18, while its paralog resides on chromosome 16.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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