Thermo Fisher Scientific Phospho-Histone H1.3 (Thr18) Polyclonal Antibody
Histone H1.3의 Thr18 인산화 형태를 특이적으로 인식하는 Rabbit Polyclonal 항체. Western blot, IHC(P), ICC/IF에 사용 가능. 고순도 액상 형태로 제공되며, -20°C에서 보관. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human HIST1H1E (Accession P10412), corresponding to amino acid residues around phosphorylated Thr18. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2815851 |
Product Specific Information
This antibody detects endogenous levels of Histone H1.3 only when phosphorylated at Thr18.
Target Information
Histones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units called nucleosomes.
The linker histone H1 interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher-order structures.
This gene is intronless and encodes a member of the histone H1 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6.
[provided by RefSeq]
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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