Thermo Fisher Scientific Phospho-RSK1 (Thr359, Ser363) Polyclonal Antibody
RSK1 단백질의 Thr359 및 Ser363 인산화 형태를 특이적으로 인식하는 폴리클로날 항체. Western blot, IHC, ICC/IF 등 다양한 분석에 사용 가능. 사람, 마우스, 랫트 반응성. 고순도 정제 및 안정적인 PBS/glycerol 저장 포맷.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:3,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Immunocytochemistry (ICC/IF)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human RPS6KA1 (Accession Q15418), corresponding to amino acid residues around phosphorylated Thr359 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2815854 |
Product Specific Information
Antibody detects endogenous levels of RSK1 p90 only when phosphorylated at PT359+S363.
Target Information
RPS6KA1 (RSK1) is a growth-factor regulated serine/threonine kinase involved in the MAPK cascade. It controls cellular proliferation and differentiation through phosphorylation of transcription factors. RPS6KA1 contains two nonidentical kinase catalytic domains and phosphorylates various substrates, including members of the MAPK signaling pathway. The activity of this protein is implicated in controlling cell growth and differentiation. Alternate transcriptional splice variants encoding different isoforms have been characterized.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
- PA5-101020_RSK1_Q15418-1_Rabbit.svg
- PA5-101020_RSK1_Q15418-1_Rabbit_PDP.jpeg
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