Thermo Fisher Scientific CD49a Monoclonal Antibody (CL7217)
인간 CD49a(Integrin alpha 1)을 인식하는 Mouse IgG1 단클론 항체로, Western blot 및 IHC(Paraffin)에서 검증됨. 단백질 A로 정제된 액상형 비결합 항체이며, 장기 보관 시 -20°C에서 안정적. 세포 부착 및 골관절염 연구에 적합.
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Applications
Western Blot (WB)
- Tested Dilution: 1 µg/mL
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:2,500–1:5,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | CL7217 |
| Immunogen | Synthetic Peptide corresponding to Human CD49a (Integrin alpha 1), UniProt ID: P56199-1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.10 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C (avoid freeze/thaw cycles) |
| Shipping Conditions | Wet ice |
| RRID | AB_2848947 |
Product Specific Information
Immunogen sequence: RQISRSFFSG TQERKVQRN
Target Information
Integrin alpha 1 (ITGA1) associates with the beta 1 (ITGB1) chain to form a heterodimer functioning as a dual laminin/collagen receptor in neural and hematopoietic cells.
ITGA1 contains a 206-amino acid I domain, three divalent cation-binding sites, and a C-terminal transmembrane domain with a short cytoplasmic tail. It has 28 potential N-glycosylation sites.
Human ITGA1 expressed in mouse fibroblast cells forms a 180-kD protein.
ITGA1 is involved in early osteoarthritic cartilage remodeling and regulates mesenchymal stem cell proliferation and cartilage production.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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