
Thermo Fisher Scientific MAPK13 Monoclonal Antibody (OTI12C3), TrueMAB
MAPK13 단백질을 인식하는 Mouse IgG2b 단일클론 항체로, WB, IHC, ICC/IF에 사용 가능. 인간 반응성으로 고순도 친화 크로마토그래피 정제. 동결건조 형태로 안정적이며 연구용으로 적합.
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- CF505782
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- pk
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI12C3 |
| Immunogen | Full length human recombinant protein of human MAPK13 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of about 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
MAPK13 (p38 delta) is a serine/threonine kinase involved in transducing extracellular signals such as cytokine and environmental stress responses. It regulates keratinocyte differentiation and is activated by phosphorylation via MAP kinase kinases or autophosphorylation through interaction with MAP3K7IP1/TAB1.
Substrates include ATF2, MEF2C, MAX, CDC25B, and p53, indicating roles in transcriptional regulation, cell cycle control, and genotoxic stress response.
Four alternatively spliced transcript variants of SAPK4 encoding distinct isoforms have been reported.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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