Thermo Fisher Scientific Secretin Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:500-1:1,000

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human Secretin. Recombinant protein control fragment (Product #RP-97261). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Secretin,uniProtId:P09683-1,ncbiNodeId:9606,antigenRange:30-118,antigenLength:121,antigenImageFileName:PA5-62279_Secretin_P09683-1_Rabbit.svg,antigenImageFileNamePDP:PA5-62279_Secretin_P09683-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.2 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2647089

Product Specific Information

Immunogen sequence: DGTFTSELSR LREGARLQRL LQGLVGKRSE QDAENSMAWT RLSAGLLCPS GSNMPILQAW MPLDGTWSPW LPPGPMVSEP AGAAAEGTL

Highest antigen sequence identity to the following orthologs: Mouse - 51%, Rat - 51%.

Target Information

Secretin belongs to the glucagon family. This protein is an endocrine hormone and its major site of production is the endocrine S cells located in the proximal small intestinal mucosa. The release of active secretin is stimulated by either fatty acids or an acidic pH in the duodenum. This hormone stimulates the secretion of bicarbonate-rich pancreatic fluids and has also been shown to regulate the growth and development of the stomach, small intestine, and pancreas. Secretin deficiency has been implicated in autistic syndrome, suggesting that the hormone could have a neuroendocrine function in addition to its role in digestion.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.