Thermo Fisher Scientific RRAS2 Polyclonal Antibody
Rabbit polyclonal antibody against human RRAS2 protein. Validated for IHC (paraffin) with 1:20–1:50 dilution. Purified by antigen affinity chromatography, supplied in PBS with glycerol and sodium azide. Suitable for cancer research and Ras signaling st...
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1:20–1:50 dilution
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human RRAS2. Recombinant protein control fragment (Product # RP-103087) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2646812 |
Product Specific Information
Immunogen sequence:
DLDHQRQVTQ EEGQQLARQL KVTYMEASAK IRMNVDQAFH ELVRV
Highest antigen sequence identity to orthologs:
- Mouse: 100%
- Rat: 100%
Target Information
RRAS2 is involved in activating mutations, and overexpression of classical Ras subfamily members (K-RAS, N-RAS, H-RAS) has been widely investigated as key events in human cancer development.
The RRAS subfamily (RRAS1, RRAS2/TC21, RRAS3/M-Ras) shares 55–60% amino acid identity with classical Ras proteins.
RRAS2 is a small GTP-binding protein of the Ras superfamily, potentially transducing growth inhibitory signals via shared effectors.
It has high oncogenic potential, with overexpression and mutations reported in multiple tumor tissues and cell lines.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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