Thermo Fisher Scientific SRSF4 Polyclonal Antibody
Human SRSF4 단백질을 인식하는 Rabbit Polyclonal 항체로, IHC(P) 및 ICC/IF에 적합합니다. 항원 친화 정제 방식으로 제조되었으며, 0.2 mg/mL 농도의 액상 형태로 제공됩니다. 단기 4°C, 장기 -20°C 보관 권장.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human SRSF4 (Product #RP-101229) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2647941 |
Product Specific Information
Immunogen sequence:
SVSKEREHAK SESSQREGRG ESENAGTNQE TRSR
Ortholog sequence identity:
- Mouse: 65%
- Rat: 62%
Target Information
Serine/arginine-rich protein 75 (SRp75) is encoded by the SRSF4 gene. SRp75 belongs to the arginine/serine-rich factor family and likely plays a role in alternative mRNA splicing.
The SR factor family contains one or more RNA recognition motifs (RRM) and an arginine/serine (RS)-rich domain. These proteins are essential for constitutive splicing and regulate alternative splicing in a concentration-dependent manner by influencing splice site selection.
Most SR proteins, including SC35 and SRp40, are localized in the nucleus, whereas SF2/ASF, SRp20, and 9G8 shuttle between the nucleus and cytoplasm, contributing to mRNA transport. The activity of SR proteins is antagonized by hnRNP A/B family members, which can alter splice site selection.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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