Thermo Fisher Scientific GPCR GPR120 Polyclonal Antibody, Biotin
Human, Mouse, Rat에서 반응하는 GPR120 폴리클로날 항체로 Western blot, ELISA, IP에 적합. Biotin으로 결합되어 검출 민감도 향상. 친화 크로마토그래피로 정제되었으며, -20°C에서 보관. 연구용으로만 사용 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | C-epitope synthetic peptide taken within amino acid region 220–300 on human FFAR4 protein |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer, pH 7.4–7.8, with 0.5% BSA, 30% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
An EST for GPR120 has been isolated from a human colon cancer library.
G-protein Coupled Receptors (GPCRs) comprise one of the largest families of signaling molecules, with more than a thousand members predicted to exist. All GPCRs share a structural motif consisting of seven membrane-spanning helices and exist in both active and inactive forms.
Various activating ligands induce conformational changes in GPCRs, triggering signaling via G-proteins and downstream effectors. Studies have also shown mechanisms involved in the negative regulation of GPCRs, which have significant implications for cellular physiology and pharmacological research.
Notably, GPCR-targeted drugs such as Zyprexa (Eli Lilly) and Claritin (Schering-Plough) have achieved major success in the mental health and allergy treatment markets.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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