Thermo Fisher Scientific eIF3D/EIF3S7 Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:2,000–1:10,000

Immunoprecipitation (IP)

• Tested Dilution: 2–5 µg/mg lysate

Product Specifications

Product Specific Information

• Recommended shelf life: 1 year from date of receipt
• Based on 100% sequence identity, this antibody is predicted to react with Mouse, Rat, Bovine, and Orangutan.

Target Information

eIF3D is a protein belonging to the largest of the eukaryotic translation initiation factor family, eukaryotic translation initiation factor-3 (eIF3).
eIF3 is a multiprotein complex composed of at least 13 different subunits. eIF3D binds to the 40S ribosomal subunit and helps maintain the 40S and 60S ribosomal subunits in a dissociated state.
It plays an important role in forming the 40S initiation complex by interacting with the ternary complex of eIF2/GTP/methionyl-tRNA and promotes mRNA binding.
eIF3D is the major RNA-binding subunit of the eIF3 complex and associates with subunit p170 of eIF-3. Ubiquitous expression of eIF3D is seen in most tissues, and it is phosphorylated upon DNA damage, likely by ATM or ATR.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.