Thermo Fisher Scientific eIF3D/EIF3S7 Polyclonal Antibody
Rabbit polyclonal antibody against human eIF3D/EIF3S7, suitable for WB and IP. Targets residues 150–200 of eIF3D. Predicted cross-reactivity with mouse, rat, bovine, and orangutan. Supplied as liquid, 1 mg/mL, stored at 4°C, shipped on wet ice.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunoprecipitation (IP) | 2–5 µg/mg lysate |
Product Specifications
| Property | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 150 and 200 of human eukaryotic translation initiation factor 3, subunit D (EIF3S7) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.0 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, predicted to react with Mouse, Rat, Bovine, and Orangutan
Target Information
eIF3D is a protein belonging to the largest eukaryotic translation initiation factor family, eIF3.
This multiprotein complex is composed of at least 13 different subunits.
eIF3D binds to the 40S ribosomal subunit and helps maintain the 40S and 60S ribosomal subunits in a dissociated state.
It plays a key role in forming the 40S initiation complex by interacting with the ternary complex of eIF2/GTP/methionyl-tRNA and promotes mRNA binding.
eIF3D is the major RNA-binding subunit of the eIF3 complex and associates with the p170 subunit of eIF3.
It is ubiquitously expressed in most tissues and is phosphorylated upon DNA damage, likely by ATM or ATR.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지 파일명: A301-758A-M_eIF3d_O15371-1_Rabbit.svg, A301-758A-M_eIF3d_O15371-1_Rabbit_PDP.jpeg)
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