Thermo Fisher Scientific CSF2 Monoclonal Antibody (OTI8F1), TrueMAB
인간 CSF2(GM-CSF)에 특이적인 마우스 단클론 항체로 Western blot에 최적화됨. 인간 시료에 반응하며 액상 형태로 제공. 항원은 E.coli에서 생산된 인간 CSF2 단백질(aa 18-144) 기반. 연구용으로만 사용 가능.
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Applications
- Western Blot (WB)
Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI8F1 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 18–144 of human CSF2 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The GM-CSF gene encodes a cytokine regulating the production, differentiation, and function of macrophages and granulocytes. The active form of the protein exists as a homodimer in the extracellular space. This gene is located in a cluster at chromosome region 5q31, associated with interstitial deletions in 5q- syndrome and acute myelogenous leukemia.
Other genes in the cluster include IL-4, IL-5, and IL-13. The gene promotes tissue inflammation, and elevated cytokine levels have been observed in SARS-CoV-2 infected patients with acute respiratory distress syndrome.
Mice lacking this gene or its receptor develop pulmonary alveolar proteinosis.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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