Thermo Fisher Scientific CD79a (B-Cell Marker) Monoclonal Antibody (SPM549)
CD79a 단백질을 인식하는 Mouse monoclonal antibody로, B세포 표지자 연구에 적합. Western blot, IHC, ICC 등 다양한 응용 가능. Human 시료 반응성, Protein A/G 정제, PBS buffer 보존. 연구용으로만 사용.
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- 973-MSM1X-P1ABX
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
| Immunocytochemistry (ICC/IF) | 2–4 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | SPM549 |
| Immunogen | Synthetic peptide corresponding to aa 202–216 (GTYQDVGSLNIADVQ) of human CD79a protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | –20°C, avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
CD79a is a disulfide-linked heterodimer that includes the B29 (CD79b) polypeptide. It functions as part of the B lymphocyte antigen receptor complex, associating with Ig-alpha and Ig-beta to enable B-cell antigen receptor expression and signaling. CD79a appears at the pre-B cell stage and remains through the plasma cell stage as an intracellular component. It is expressed in most precursor B-cell acute leukemias, B-cell lines, B-cell lymphomas, and some myelomas, but absent in myeloid or T-cell lines. Diseases associated with CD79a include Agammaglobulinemia 3 and Agammaglobulinemia, Non-Bruton type.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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