Thermo Fisher Scientific CD79a (B-Cell Marker) Monoclonal Antibody (SPM549)
CD79a 단백질을 표적으로 하는 인간 반응성 마우스 단클론 항체로, B 세포 마커 분석에 적합. Western blot, IHC, ICC 등 다양한 응용 가능. 고순도 Protein A/G 정제, 액상 형태로 안정적 보관. 연구용 전용 제품.
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Thermo Fisher Scientific CD79a (B-Cell Marker) Monoclonal Antibody (SPM549)
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
| Immunocytochemistry (ICC/IF) | 2–4 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | SPM549 |
| Immunogen | Synthetic peptide corresponding to aa 202–216 (GTYQDVGSLNIADVQ) of human CD79a protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
CD79a is a disulphide-linked heterodimer that includes the B29 (CD79b) polypeptide. It forms part of the B lymphocyte antigen receptor complex, associating with Ig-alpha and Ig-beta, which are essential for receptor expression and function. CD79a appears at the pre-B cell stage and persists through to the plasma cell stage as an intracellular component. It is expressed in most acute leukemias of precursor B-cell type, B-cell lines, B-cell lymphomas, and some myelomas, but absent in myeloid or T-cell lines. Diseases associated with CD79a include Agammaglobulinemia 3 and Non-Bruton type Agammaglobulinemia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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