Thermo Fisher Scientific LPHN2 Polyclonal Antibody
Rabbit polyclonal antibody against human LPHN2, validated for IHC (Paraffin). Recognizes N-terminal extracellular domain. High specificity and purity via antigen affinity chromatography. Supplied in PBS with sodium azide, 1 mg/mL, for research use only.
- 카탈로그번호
- PA533905
- 판매단위
- pk
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 18–45 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 16 amino acid peptide from N-terminal extracellular domain of human LPHN2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2551273 |
Product Specific Information
Percent identity with other species by BLAST analysis:
- Human, Gibbon, Monkey: 100%
- Gorilla, Marmoset, Mouse: 94%
- Rat, Dog, Panda: 88%
Target Information
The Latrophilin family of G protein-coupled receptors consists of three members: latrophilin-1, 2, and 3, each with distinct tissue distribution and function.
Latrophilin-1 acts as a receptor for α-latrotoxin, a component of black widow spider venom, triggering synaptic vesicle exocytosis via Ca²⁺-dependent and -independent mechanisms.
Latrophilin-1 is abundant in the brain and present in endocrine cells. Latrophilin-3 is also brain-specific, whereas latrophilin-2 expression is ubiquitous.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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