Thermo Fisher Scientific PCDHGC5 Monoclonal Antibody (OTI1G6), TrueMAB
인간 PCDHGC5 단백질을 표적으로 하는 단일클론 항체로, Western blot에 최적화되어 있습니다. 마우스 IgG2a 형식이며, 액상 형태로 1 mg/mL 농도 제공. 고순도 친화 크로마토그래피 정제 제품으로 연구용에 적합합니다.
- 카탈로그번호
- TA807812
- 판매단위
- pk
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Applications
- Western Blot (WB)
Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1G6 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 35–258 of human PCDHGC5 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These clusters have an immunoglobulin-like organization, suggesting a novel mechanism for regulation and expression. The gamma cluster includes 22 genes divided into 3 subfamilies:
- Subfamily A: 12 genes
- Subfamily B: 7 genes + 2 pseudogenes
- Subfamily C: 3 genes
Each variable region exon encodes the extracellular region (6 cadherin ectodomains and a transmembrane region), while constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins likely play critical roles in establishing and maintaining specific cell-cell connections in the brain. Alternative splicing has been described for gamma cluster genes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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