Thermo Fisher Scientific PCDHGC5 Monoclonal Antibody (OTI2F3), TrueMAB
인간 PCDHGC5 단백질(aa 35-258)을 인식하는 Mouse monoclonal antibody입니다. Western blot에서 검증되었으며, 1 mg/mL 농도의 액상 형태로 제공됩니다. PBS, BSA, glycerol buffer에 보관되며 -20°C에서 안정적으로 저장 가능합니다.
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Applications
- Western Blot (WB): Tested dilution 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2F3 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 35–258 of human PCDHGC5 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The PCDHGC5 gene belongs to the protocadherin gamma gene cluster, one of three related clusters located on chromosome 5. These clusters exhibit an immunoglobulin-like organization, suggesting unique regulatory mechanisms. The gamma cluster includes 22 genes divided into three subfamilies:
- Subfamily A: 12 genes
- Subfamily B: 7 genes and 2 pseudogenes
- Subfamily C: 3 genes
Each variable region exon encodes the extracellular domain with six cadherin ectodomains and a transmembrane region, while constant region exons encode the shared cytoplasmic region. These neural cadherin-like cell adhesion proteins are believed to play an essential role in forming specific cell-cell connections in the brain. Alternative splicing events have been reported for the gamma cluster genes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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