Thermo Fisher Scientific PCDHGC5 Monoclonal Antibody (OTI1D7), TrueMAB
PCDHGC5 단백질을 인식하는 Mouse IgG1 단일클론 항체. Western blot에 최적화되어 있으며, 인간 시료에 반응. 고순도 친화 크로마토그래피 정제, PBS/BSA/glycerol 완충액에 보관. 연구용으로만 사용 가능.
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Applications
- Western Blot (WB): Tested dilution 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1D7 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 35–258 of human PCDHGC5 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression.
The gamma gene cluster includes 22 genes divided into 3 subfamilies (A, B, and C). Each variable region exon encodes the extracellular region with six cadherin ectodomains and a transmembrane region, while the constant region exons encode the common cytoplasmic region.
These neural cadherin-like cell adhesion proteins likely play a critical role in establishing and maintaining specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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