Thermo Fisher Scientific mGluR1 Polyclonal Antibody
mGluR1 단백질을 인식하는 토끼 폴리클로날 항체로, Western blot 등 연구용에 적합합니다. C-말단 영역에서 유래한 합성 펩타이드를 면역원으로 사용하였으며, 비결합(Unconjugated) 상태의 액상 제품입니다. -20°C 보관, Wet ice 배송 조건입니다.
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Applications
- Western Blot (WB): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide derived from the C-terminal region of the mGluR5 and mGluR1a |
| Conjugate | Unconjugated |
| Form | Liquid |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
Target Information
Glutamate is the main excitatory neurotransmitter in the brain. It acts on ligand-gated receptor channels such as NMDA, AMPA, and kainate receptors involved in fast excitatory synaptic transmission. Additionally, glutamate regulates enzymes producing second messengers via metabotropic glutamate receptors (mGluRs) coupled to G-proteins.
Group-I receptors (mGluR1a and mGluR5) stimulate phospholipase C, increasing phosphoinositide turnover and intracellular calcium release.
Group-II (mGluR2, mGluR3) and Group-III receptors inhibit adenylyl cyclase activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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