Thermo Fisher Scientific GORAB Monoclonal Antibody (OTI4A4), TrueMAB
GORAB 단백질을 인식하는 Mouse IgG1 단클론 항체로 Western Blot과 Flow Cytometry에 적합함. 인간 시료 반응성, 고순도 Affinity chromatography 정제. 안정한 액상 형태로 PBS/BSA/glycerol buffer에 보존되며 연구용으로 사용.
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Thermo Fisher Scientific GORAB Monoclonal Antibody (OTI4A4), TrueMAB
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4A4 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 35–394 of human GORAB produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
TCEB1, also known as protein elongin C, is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B, and C, which activate elongation by RNA polymerase II by suppressing transient pausing within transcription units.
Elongin A functions as the transcriptionally active component, while elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis and forms a stable complex with elongins B and C.
The von Hippel–Lindau tumor suppressor protein binds to elongins B and C, inhibiting transcription elongation. Western blot analyses using different antibodies confirm consistent molecular weight results for this protein target.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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