Thermo Fisher Scientific TMEM173 Monoclonal Antibody (OTI4E12), TrueMAB
TMEM173(STING) 단백질을 인식하는 마우스 단클론 항체로, Western blot과 IHC(P)에서 검증됨. HEK293T 세포에서 발현된 full-length human TMEM173을 면역원으로 사용. 1 mg/mL 농도의 액상 형태이며, -20°C에서 보관. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4E12 |
| Immunogen | Full length human recombinant protein of human TMEM173 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Additional Formats:
Target Information
STING (TMEM173) is a 379 amino acid signaling protein involved in innate immune signaling. It activates NF-kappa-B and IRF3 transcription pathways to induce type I interferons (IFN-α and IFN-β), establishing an antiviral state. STING may act as a translocon influencing interferon induction and mediating apoptotic signaling via MHC-II association. It is located in the endoplasmic reticulum membrane, cell membrane, and mitochondrial outer membrane, and is ubiquitously expressed in most tissues.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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