Thermo Fisher Scientific PDE2A Polyclonal Antibody
PDE2A 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB, IHC, ICC/IF, ELISA 등 다양한 응용에 적합. 인간, 마우스, 랫트 반응성. 고순도 Affinity chromatography 정제, 안정적 액상 형태로 연구용 사용에 최적화됨.
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Thermo Fisher Scientific PDE2A Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (IHC) | 1:50–1:250 |
| Immunocytochemistry (ICC/IF) | 1:50–1:250 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
| Immunomicroscopy (IM) | 1:50–1:200 |
| Fluorescence Resonance Energy Transfer (FRET) | 1:50–1:250 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to unique C-terminal amino acid sequence on PDE2A gene |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer (pH 7.4–7.8) with 0.5% BSA, 30% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
PDE2A (phosphodiesterase 2A) is a 100 kD cyclic nucleotide phosphodiesterase (PDE) with three reported isoforms (PDE2A1, PDE2A2, PDE2A3) derived from a single gene via alternative splicing. PDE2A degrades both cAMP and cGMP, with higher efficacy toward cGMP. It is expressed in various tissues, predominantly in the brain (cerebellum and neocortex). PDE2A has been implicated in erectile dysfunction and regulation of endothelial cell barrier transport.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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