Thermo Fisher Scientific PDE2A1 Polyclonal Antibody, Biotin
Thermo Fisher Scientific의 PDE2A1 Polyclonal Antibody, Biotin은 인간, 마우스, 랫트 등 다양한 종에 반응하는 Rabbit IgG 기반 항체입니다. Western blot, IHC, ELISA, IP 등에 사용 가능하며, Biotin 결합형으로 높은 특이성과 안정성을 제공합니다. 연구용으로만 사용됩니다.
- 카탈로그번호
- PD2A1-BIOTIN
- 판매단위
- pk
카탈로그
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (IHC) | 1:50–1:250 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to region within amino acids 1–50 on N-terminus of human PDE2A1 protein |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer, pH 7.4–7.8, with 30% glycerol, 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | –20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
PDE2A (phosphodiesterase 2A) is a 100 kDa cyclic nucleotide phosphodiesterase (PDE). Three isoforms—PDE2A1, PDE2A2, and PDE2A3—arise from a single gene via alternative splicing. PDE2A degrades both cAMP and cGMP, with greater efficacy for cGMP. It is expressed in multiple tissues, predominantly in the brain (cerebellum and neocortex). PDE2A is implicated in penile erectile dysfunction and regulation of fluid and inflammatory cell transport across endothelial barriers.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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