Thermo Fisher Scientific Phospho-MAP2K4 (Ser257) Monoclonal Antibody (G.674.10)
MAP2K4의 인산화된 Ser257을 인식하는 Rabbit 모노클로날 항체로, WB 및 Flow Cytometry에 사용 가능. 고순도 Affinity chromatography 정제, 안정적인 액상 형태. 인체, 마우스, 랫 등 다양한 종에 반응하며, 연구용으로 적합.
- 판매단위
- pk
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Flow Cytometry (Flow) | 1:400 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Monoclonal |
| Type | Antibody |
| Clone | G.674.10 |
| Immunogen | Synthetic phosphopeptide corresponding to residues surrounding pSer257/Thr261 of human SEK1/MKK4 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Affinity chromatography |
| Storage Buffer | 0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol |
| Contains | <0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_10984339 |
Product Specific Information
It is not recommended to aliquot this antibody.
Target Information
MAP2K4 (MEK4) is a serine/threonine kinase of the STE7 family that phosphorylates and activates JNK1/2 and p38. It preferentially phosphorylates the tyrosine residues of JNKs and mediates various physiological and pathophysiological processes such as responses to cellular stress and inflammatory cytokines. MAP2K4 plays important roles in carcinogenesis, with loss-of-function mutations found in lung and pancreatic tumors, while also exhibiting pro-oncogenic roles in certain contexts.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지 파일명: MA5-14826_MAP2K4_P45985-1_Rabbit.svg, MA5-14826_MAP2K4_P45985-1_Rabbit_PDP.jpeg)
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