Thermo Fisher Scientific DUSP22 Polyclonal Antibody
DUSP22 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, 인간 및 다양한 종에 반응합니다. IHC(P) 등 연구용으로 사용되며, 항원 친화 크로마토그래피로 정제된 고순도 제품입니다. 4°C 단기, -20°C 장기 보관을 권장합니다.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): Tested dilution 4 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Bovine, Horse, Human, Non-human primate, Rabbit |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 17 amino acid peptide from internal region of human DUSP22 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2550869 |
Product Specific Information
Percent identity with other species by BLAST analysis:
Human, Gorilla, Gibbon, Monkey, Marmoset, Elephant, Bovine, Horse, Rabbit (100%)
Mouse, Rat, Panda, Turkey, Chicken (94%)
Target Information
Mitogen-activated protein (MAP) kinases are a large class of proteins involved in signal transduction pathways that are activated by a range of stimuli and mediate a number of physiological and pathological changes in the cell.
Dual specificity phosphatases (DSPs) are a subclass of the protein tyrosine phosphatase (PTP) gene superfamily, selective for dephosphorylating critical phosphothreonine and phosphotyrosine residues within MAP kinases.
DSP gene expression is induced by various growth factors and cellular stresses, thereby negatively regulating MAP kinase superfamily members including MAPK/ERK, SAPK/JNK, and p38.
DUSP22 dephosphorylates ERK2 MAP kinase and JNK. DUSP22 is expressed most highly in thymus, and also detectable in monocytes and lymphocytes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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